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Importantly, activation of the Nrf2heme oxygenase-1 (HO-1) pathway via cobalt protoporphyrin IX reversed changes, normalizing corticosterone levels and receptor expression

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Regrettably, whether the ventricular diastolic function was improved, and the intracardiac pressure was decreased were not be evaluated in this study

In humans also MGST3 is a member of MAPEG, together with microsomal prostaglandin E synthase 1 (MPGES1) and 5-lipoxygenase activating protein (FLAP)